In the far north of Madagascar, the Antsiranana region is a tourism portal, notably thanks to the proximity of the island of Nosy Be. With luxury hotels and other types of prestigious accommodation, Nosy Be is the hotspot for seaside tourism in the country. Apart from Nosy Be, many other interesting tourist attractions can be found in the area. Other paradise islands, nature reserves, and a wide variety of entertainment can also enhance a visit to the region. The cities of Diego and Nosy Be are both accessible by plane, but some people prefer to choose the roads in order to discover the landscapes and the lives of the local people of the region. Note, however, that the trip is particularly long as Antsiranana is located nearly 1,000 km from Antananarivo. The northern region of Madagascar is particularly rich in terms of biodiversity, and the majority of the ecosystems of the region’s nature reserves are endemic.